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When a compound has no completed human trial, there is by definition no safety data in any subgroup no pregnancy data, no hepatic-impairment data, no interaction data with common metabolic or endocrine medications

Heres why: Ongoing Absorption Issues: Many people have conditions that impair their ability to absorb B12 from food or oral supplements, such as pernicious anemia or gastrointestinal disorders

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The ALAD protein, which is a known target for TRXs and NTRC, was used as a positive control ( Figures 5B, C )